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KMID : 0942820120110010023
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Journal of Korean Brain Tumor Society
2012 Volume.11 No. 1 p.23 ~ p.27
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Assessment of Quality of Life after Resection of Petroclival Meningiomas
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Kim Moon-Seok
Yang Seung-Ho
Kim Il-Sup
Hong Jae-Taek
Sung Jae-Hoon
Son Byung-Chul
Lee Sang-Won
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Abstract
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Objectives: This study was performed to assess the quality of life (QoL) of the patients with petroclival meningioma treated with surgery with/without radiotherapy.
Methods: From 2005 to 2010, 12 patients with newly diagnosed petroclival meningioma underwent surgery at a single institution. The status of preoperative and postoperative (6 months) QoL was assessed using EORTC QLQ-C30 and Brain Cancer Module (BN20).
Results: The most frequent preoperative symptoms were headache and dizziness. Total, subtotal, and partial resections were achieved in five, two, and five patients, respectively. Radiation therapy was performed in four patients with subtotal or partial resection. The postoperative complications were cranial nerve palsy (n=3), hemiparesis (n=2), and meningitis (n=2). Delayed hydrocephalus was found in two patients treated with additional radiosurgery. Motor dysfunction, bladder control, nausea/vomiting, dyspnea, insomnia, appetite loss, and constipation deteriorated and worsened the status of patients’ QoL. However, headache, future uncertainty, and visual disorder improved.
Conclusion: Postoperative QoL of the patients with petroclival meningiomas could be associated with surgery with/without radiation-related morbidity. Besides the treatment-associated morbidity and mortality rates, QoL issues should be evaluated in the research of skull base tumors in the future.
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KEYWORD
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Petroclival meningioma, Quality of life, Skull base surgery, Morbidity, EORTC QLQ-C30
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